Buckyballs conjugated with nucleic acid sequences identifies microorganisms in live cell assays

Buckyballs conjugated with nucleic acid sequences identifies microorganisms in live cell assays

BACKGROUND Rapid identification of bacteria can play an important role at the point of care, evaluating the health of the ecosystem, and discovering spatiotemporal distributions of a bacterial community. We introduce a method for rapid identification of bacteria in live cell assays based on cargo delivery of a nucleic acid sequence and demonstrate how a mixed culture can be differentiated using...

Identification of Microorganisms Using Nucleic Acid Probes

Identification of Microorganisms Using Nucleic Acid Probes

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A Conjugated Nucleic Acid of Pancreas

A recent preliminary communication by Feulgenl on a conjugated nucleic acid of pancreas prompts me to publish my own results on the same subject. Feulgen prepared a nucleic acid from pancreas by enzymatic digestion of p-nucleoprotein. This acid could be split into phosphoric acid, levulinic acid, furfurol, thymine, cytosine, guanine, and adenine. He found that an alkali salt of guanylic acid co...

Atypical Acid-fast Microorganisms: I. Nucleic Acid Fraction.

This paper deals with a preliminary study of the nucleic acid fraction of ten representative strains of atypical acid-fast bacilli isolated from sputum and gastric contents of patients with proven or suspected tuberculosis (Loesch and Petrik, 1939). Strains Ya and Fe were isolated from cultures which also contained colonies of virulent human-type tubercle bacilli. Cultures from which the remain...